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Carlo Maj, PhD



Research interest

Carlo Maj is interested in polygenic analyses of multifactorial traits. 

Scientific Vita

since 2018 Researcher at the Institute for Genomic Statistics and Bioinformatics, University Hospital Bonn, Germany

2014-2017 Bioinformatician at IRCCS Saint John of God, Clinical Research Centre for Neuropsychiatry Diseases , Brescia, Italy

2013-2013 Visiting Scholar at Weldon School of Biomedical Engineering, Purdue University, Indiana, USA

2011-2014 PhD Student in Computer Science at the University of Milano-Bicocca, Italy

2009-2013 Research assistant at the Institute of Biomedical Technologies ITBCNR, Segrate (MI), Italy 



[1] Stefano Beretta, Carlo Maj, and Ivan Merelli. “Rank miRNA: a web tool for identifying polymorphisms altering miRNA target sites”. In: Procedia Computer Science 108 (2017), pp. 1125–1134.

[2] Nadia Cattane, Alessandra Minelli, Elena Milanesi, Carlo Maj, Stefano Bignotti, Marco Bortolomasi, Luisella Bocchio Chiavetto, and Massimo Gennarelli. “Altered gene expression in schizophrenia: findings from transcriptional signatures in fibroblasts and blood”. In:PloS one 10.2 (2015), e0116686.

[3] Chiara Congiu, Alessandra Minelli, Cristian Bonvicini, Marco Bortolomasi, Riccardo Sartori, Carlo Maj, Catia Scassellati, Giuseppe Maina, Luigi Trabucchi, Matilde Segala, et al. “The role of the potassium channel gene KCNK2 in major depressive disorder”. In:Psychiatry research 225.3 (2015), pp. 489–492.

[4] Luca Corolli, Carlo Maj, Fabrizio Marini, Daniela Besozzi, and Giancarlo Mauri. “An excursion in reaction systems: From computer science to biology”. In:Theoretical computer science 454 (2012), pp. 95–108.

[5] Daniele D’Agostino, Giulia Pasquale, Andrea Clematis, Carlo Maj, Ettore Mosca, Luciano Milanesi, and Ivan Merelli. “Parallel solutions for voxel based simulations of reaction-diffusion systems”. In:BioMed Research International 2014 (2014).

[6] Vu Dinh, Carlo Maj, Giancarlo Mauri, Gregery T Buzzard, and Ann E Rundell. Mapping the parameter space with oscillatory and steady state system dynamics.2013.

[7] E Maffioletti, C Congiu, C Bonvicini, C Maj, A Minelli, M Bortolomasi, G Maina, M Gennarelli, and L Bocchio-Chiavetto. “P. 2. a. 011 Study of microRNA-related single-nucleotide polymorphisms in major depression”. In: European Neuropsychopharmacology 25 (2015), S381.

[8] Elisabetta Maffioletti, Annamaria Cattaneo, Gianluca Rosso, Giuseppe Maina, Carlo Maj, Massimo Gennarelli, Daniela Tardito, and Luisella Bocchio-Chiavetto. “Peripheral whole blood microRNA alterations in major depression and bipolar disorder”. In: Journal of affective disorders 200 (2016), pp. 250–258.

[9] Elisabetta Maffioletti, Alessandro Salvi, Isabel Conde, Carlo Maj, Massimo Gennarelli, Giuseppina De Petro, and Luisella Bocchio-Chiavetto. “Study of the in vitro modulation exerted by the antidepressant drug escitalopram on the expression of candidate microRNAs and their target genes”. In: Molecular and Cellular Neuroscience 85 (2017), pp. 220–225.

[10] Carlo Maj, Alessandra Minelli, Edoardo Giacopuzzi, Emilio Sacchetti, and Massimo Gennarelli. “The role of metabotropic glutamate receptor genes in schizophrenia”. In: Current neuropharmacology 14.5 (2016), pp. 540–550

[11] Carlo Maj, Ettore Mosca, Ivan Merelli, Giancarlo Mauri, and Luciano Milanesi. “Sensitivity analysis for studying the relation between biochemical reactions and metabolic phenotypes”. In: Journal of bioinformatics and computational biology 11.01 (2013), p. 1340002.

[12] Carlo Maj, Claudia Raibulet, and Giancarlo Mauri. “Self-adaptive simulation time for sensitivity analysis of a stochastic computational model”. In: Control Conference (ECC), 2014 European. IEEE. 2014, pp. 2072–2077.

[13] Carlo Maj, Elena Milanesi, Massimo Gennarelli, Luciano Milanesi, et al. Epistasis analysis reveals associations between gene variants and bipolar disorder. Tech. rep. PeerJ Preprints, 2017.

[14] Ivan Merelli, Dario Pescini, Ettore Mosca, Paolo Cazzaniga, Carlo Maj, Giancarlo Mauri, and Luciano Milanesi. “Grid computing for sensitivity analysis of stochastic biological models”. In: International Conference on Parallel Computing Technologies. Springer, Berlin, Heidelberg. 2011, pp. 62–73.

[15] Elena Milanesi, Carlo Maj, Luisella Bocchio-Chiavetto, and Elisabetta Maffioletti. “Nanomedicine in Psychiatry: New Therapeutic Opportunities from Research on Small RNAs”. In: Drug development research 77.8 (2016), pp. 453–457.

[16] Elena Milanesi, Irena Voinsky, Adva Hadar, Carlo Maj, John R Kelsoe, Tatyana Shekhtman, Peter Zandi, Fernando Goes, James B Potash, Michael Greshovits, et al. “RNA-Sequencing of Bipolar Disorder Patients Lymphoblastoid Cell Lines Implicates A Novel Neurotrophic Factor In The Efficacy of Lithium As Mood Stabilizing Drug”. In: European Neuropsychopharmacology 27 (2017), S391–S392.

[17] Ettore Mosca, Roberta Alfieri, Carlo Maj, Annamaria Bevilacqua, Gianfranco Canti, and Luciano Milanesi. “Computational modeling of the metabolic States regulated by the kinase akt”. In: Frontiers in physiology 3 (2012), p. 418.

[18] Giulia Pasquale, Carlo Maj, Andrea Clematis, Ettore Mosca, Luciano Milanesi, Ivan Merelli, and Daniele D’Agostino. “A CUDA implementation of the Spatial TAU-leaping in Crowded Compartments (STAUCC) simulator”. In: Parallel, Distributed and Network-Based Processing (PDP), 2014 22nd Euromicro International Conference on. IEEE. 2014, pp. 609– 616.

[19] Daniele Ramazzotti, Carlo Maj, and Marco Antoniotti. “A Model of Colonic Crypts using SBML Spatial”. In: arXiv preprint arXiv:1309.7692 (2013). 

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